Polymorphism in the Prolactin Promoter and Its Association with Growth Traits in Chickens

The pituitary hormone prolactin has a wide variety of functions involving growth, behavioral, and ovarian activities in chickens. The objectives of the present study were to identify polymorphisms in the prolactin promoter and estimate their effects on growth traits in White Leghorn chickens. Among...

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Veröffentlicht in:	Biochemical genetics 2011-06, Vol.49 (5-6), p.385-394
Hauptverfasser:	Bhattacharya, T. K., Chatterjee, R. N., Sharma, R. P., Niranjan, M., Rajkumar, U., Reddy, B. L. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biochemistry Biomedical and Life Sciences Biomedicine Birds Body weight Body Weight - genetics Chickens Chickens - genetics Chickens - growth & development Gene Expression Profiling Genetic Association Studies Haplotypes Human Genetics Likelihood Functions Medical Microbiology Molecular Sequence Data Polymorphism, Single Nucleotide Poultry Prolactin - genetics Prolactin - metabolism Promoter Regions, Genetic Sequence Alignment Sequence Analysis, DNA Sexual Maturation - genetics Sexual maturity Zoology
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Zusammenfassung:	The pituitary hormone prolactin has a wide variety of functions involving growth, behavioral, and ovarian activities in chickens. The objectives of the present study were to identify polymorphisms in the prolactin promoter and estimate their effects on growth traits in White Leghorn chickens. Among 28 haplotypes found, the h1 haplotype was predominant. Body weight at 16 and 64 weeks and age at sexual maturity were significantly associated with haplotype combinations ( P
ISSN:	0006-2928 1573-4927
DOI:	10.1007/s10528-010-9415-3