Controllable disintegration of temperature-responsive self-assembled multilayer film based on polybetaine

Critical disintegration temperature ( T cd) of PDMAPS/PAA multilayer films versus pH of buffer solution and controllable disintegration of temperature-responsive multilayer films. [Display omitted] ► The temperature-disintegrable multilayer films of PDMAPS and PAA were firstly reported. ► The disintegration of PDMAPS/PAA multilayer films could be well controlled. ► Free-standing multilayer films were successfully prepared using PDMAPS/PAA as a sacrificial sublayer. A layer-by-layer (LbL) self-assembly technique was used to construct temperature-responsive multilayer films of polybetaine poly-3-dimethyl(methacryloyloxyethyl) ammonium propane sulfonate (PDMAPS) and poly(acrylic acid) (PAA). The assembly and disintegration behaviors of PDMAPS/PAA multilayer films were investigated by quartz crystal microbalance (QCM) and atomic force microscopy (AFM). The results indicated that the assembly behaviors of PDMAPS/PAA multilayer films could be well regulated by the pH and temperature of dipping solutions. The disintegration of PDMAPS/PAA multilayer films could be well controlled by varying the disintegration temperature ( T d) and the pH of buffer solution. The critical disintegration temperature ( T cd) decreased with increasing pH of buffer solution used. The ionization of carboxylic acid groups (COOH) of PAA and the breakage of intra-chain associations of PDMAPS in multilayer films are two main reasons for the film disintegration. Based on the controllable disintegration of the PDMAPS/PAA multilayer, free-standing multilayer films were successfully prepared by LbL self-assembly of poly(4-vinylpyridiniomethanecarboxylate) (PVPMC) and PAA using PDMAPS/PAA as a sacrificial sublayer.