Management of anal canal carcinoma

Although anal canal squamous cell carcinoma is rare, the general practitioner should consider this diagnosis in a patient with persistent lower abdominal symptoms. While classically observed in older women, an increased incidence is also seen in HIV-positive patients or patients with a history of hu...

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Veröffentlicht in:Revue médicale suisse 2011-05, Vol.7 (296), p.1144-1148
Hauptverfasser: Thang, N-N Tran, Cochet, S, George, A-C, Betz, M, Roth, A
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Sprache:fre
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Zusammenfassung:Although anal canal squamous cell carcinoma is rare, the general practitioner should consider this diagnosis in a patient with persistent lower abdominal symptoms. While classically observed in older women, an increased incidence is also seen in HIV-positive patients or patients with a history of human papillomavirus infection. Initial diagnosis and local work-up require assessment by a proctologist. Standard curative treatment combines radiotherapy with 5-FU- and MMC-based chemotherapy. Salvage surgery should be discussed in case of local relapse. The general practitioner, the proctologist and the radiation oncologist, all participate in post-treatment surveillance.
ISSN:1660-9379