Management of anal canal carcinoma
Although anal canal squamous cell carcinoma is rare, the general practitioner should consider this diagnosis in a patient with persistent lower abdominal symptoms. While classically observed in older women, an increased incidence is also seen in HIV-positive patients or patients with a history of hu...
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Veröffentlicht in: | Revue médicale suisse 2011-05, Vol.7 (296), p.1144-1148 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | fre |
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Zusammenfassung: | Although anal canal squamous cell carcinoma is rare, the general practitioner should consider this diagnosis in a patient with persistent lower abdominal symptoms. While classically observed in older women, an increased incidence is also seen in HIV-positive patients or patients with a history of human papillomavirus infection. Initial diagnosis and local work-up require assessment by a proctologist. Standard curative treatment combines radiotherapy with 5-FU- and MMC-based chemotherapy. Salvage surgery should be discussed in case of local relapse. The general practitioner, the proctologist and the radiation oncologist, all participate in post-treatment surveillance. |
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ISSN: | 1660-9379 |