Generating high-quality protein binders: a large screening effort pays off
A large-scale, multifaceted screening and validation strategy combining traditional and recombinant antibody technologies yielded a broad spectrum of validated protein binders with high binding affinity and specificity applicable to many fields in proteome research.
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| Veröffentlicht in: | Nature methods 2011-07, Vol.8 (7), p.545-546 |
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| container_title | Nature methods |
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| creator | Nollau, Peter |
| description | A large-scale, multifaceted screening and validation strategy combining traditional and recombinant antibody technologies yielded a broad spectrum of validated protein binders with high binding affinity and specificity applicable to many fields in proteome research. |
| doi_str_mv | 10.1038/nmeth.1632 |
| format | Article |
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| source | MEDLINE; Nature; SpringerNature Journals |
| subjects | 631/1647/338 631/1647/664 Animals Antibodies, Monoclonal - immunology Binders Bioinformatics Biological Microscopy Biological Techniques Biomedical and Life Sciences Biomedical Engineering/Biotechnology DNA microarrays Humans Life Sciences Monoclonal antibodies news-and-views Physiological aspects Protein Array Analysis - methods Protein Binding Proteins Proteins - chemistry Proteins - immunology Proteome Proteomics Reproducibility of Results Scientific method src Homology Domains - immunology |
| title | Generating high-quality protein binders: a large screening effort pays off |
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