Biologic Variation of a Novel Cardiac Troponin I Assay

Biologic Variation of a Novel Cardiac Troponin I Assay

[...] we evaluated BV for a recently developed high-sensitivity cardiac troponin I (hs-cTnI) assay (2 ) from Beckman Coulter. The index of individuality was computed as (CVA2 + CVI2)1/2/CVG, where CVA is the analytical CV, CVI is the intraindividual CV, and CVG is the interindividual CV. Because the...

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Veröffentlicht in:Clinical chemistry (Baltimore, Md.) Md.), 2011-07, Vol.57 (7), p.1080-1081
Hauptverfasser: VASILE, Vlad C, SAENGER, Amy K, KRONING, Jean M, KLEE, George G, JAFFE, Allan S
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Analytical, structural and metabolic biochemistry
Biological and medical sciences
Biomarkers
Cardiology
Cardiovascular Diseases - diagnosis
Female
Fundamental and applied biological sciences. Psychology
Generalized linear models
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Molecular biophysics
Reference Values
Troponin I - blood
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Zusammenfassung:[...] we evaluated BV for a recently developed high-sensitivity cardiac troponin I (hs-cTnI) assay (2 ) from Beckman Coulter. The index of individuality was computed as (CVA2 + CVI2)1/2/CVG, where CVA is the analytical CV, CVI is the intraindividual CV, and CVG is the interindividual CV. Because the data were skewed, RCVs were calculated after lognormal transformation.
ISSN:0009-9147
1530-8561
DOI:10.1373/clinchem.2011.162545