Subclinical elevations of thyroid-stimulating hormone and assisted reproductive technology outcomes

The prevalence of moderately elevated TSH levels consistent with subclinical hypothyroidism (2.5–4.0 μIU/mL) was 23% in a cohort of 1,231 women pursuing assisted reproductive technologies. Preconception elevated levels of TSH were associated with diminished ovarian reserve but were not associated wi...

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Veröffentlicht in:	Fertility and sterility 2011-06, Vol.95 (8), p.2634-2637
Hauptverfasser:	Michalakis, Konstantinos G., M.D, Mesen, Tolga B., M.D, Brayboy, Lynae M., M.D, Yu, Bo, M.D, Richter, Kevin S., Ph.D, Levy, Michael, M.D, Widra, Eric, M.D, Segars, James H., M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis of Variance Asymptomatic Diseases autoimmunity Biological and medical sciences Biomarkers - blood Birth control Chi-Square Distribution diminished ovarian reserve Endocrinopathies Female Gynecology. Andrology. Obstetrics Humans Hypothyroidism - blood Hypothyroidism - complications Hypothyroidism - diagnosis Hypothyroidism - physiopathology Internal Medicine Medical sciences Non tumoral diseases. Target tissue resistance. Benign neoplasms Obstetrics and Gynecology Ovary - physiopathology Pregnancy Pregnancy Complications - etiology Pregnancy Outcome Pregnancy Rate Reproductive Techniques, Assisted - adverse effects Retrospective Studies Sterility. Assisted procreation subclinical hypothyroidism Thyroid. Thyroid axis (diseases) Thyrotropin - blood Treatment Outcome TSH United States Up-Regulation
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Zusammenfassung:	The prevalence of moderately elevated TSH levels consistent with subclinical hypothyroidism (2.5–4.0 μIU/mL) was 23% in a cohort of 1,231 women pursuing assisted reproductive technologies. Preconception elevated levels of TSH were associated with diminished ovarian reserve but were not associated with adverse assisted reproductive technology or pregnancy outcomes.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/j.fertnstert.2011.02.056