Carbohydrate Does Not Augment Exercise-Induced Protein Accretion versus Protein Alone

We tested the thesis that CHO and protein coingestion would augment muscle protein synthesis (MPS) and inhibit muscle protein breakdown (MPB) at rest and after resistance exercise. Nine men (age=23.0±1.9 yr, body mass index=24.2±2.1 kg·m) performed two unilateral knee extension trials (four sets×8-12 repetitions to failure) followed by consumption of 25 g of whey protein (PRO) or 25 g of whey protein plus 50 g of maltodextrin (PRO+CARB). Muscle biopsies and stable isotope methodology were used to measure MPS and MPB. The areas under the glucose and insulin curves were 17.5-fold (P