A characteristic of Triple-negative Breast Cancer from Ultrasonic Findings for Consideration

From diagnosis it was decided how to adjuvant therapy with use of the hormone receptor (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2.) Triple negative (TN) breast cancer is defined as a subtype that is negative for estrogen receptor, progesterone receptor, a...

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Veröffentlicht in:Japanese Journal of Medical Ultrasound Technology 2010/12/01, Vol.35(6), pp.635-640
Hauptverfasser: Yoshida, Kayo, Shirai, Hideaki, Sakurai, Miki, Asaishi, Kazuaki
Format: Artikel
Sprache:eng ; jpn
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Zusammenfassung:From diagnosis it was decided how to adjuvant therapy with use of the hormone receptor (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2.) Triple negative (TN) breast cancer is defined as a subtype that is negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. Patients with TN breast cancer tend to have a poor prognosis. Only chemotherapy is expected to be effective because no targeted therapies have been established. A characteristic of TN breast cancer can be determined by comparing the ultrasonic findings with non-TN breast cancer. The ultrasonic findings of 57 cases of TN breast cancer and 634 cases of non-TN breast cancer (January, 2006 to December, 2008 at Sapporo Kotoni Breast Clinic) out of 703 cases of primary breast cancer were investigated using the “Guideline for Breast Ultrasound–Management and Diagnosis, 2nd Edition”. In conclusion the shape, boundary zone, echo level , and posterior echo recognized a significant difference by χ2 certificate examination. It is suggested that an expanded growth tumor may be a characteristic of TN breast cancer.
ISSN:1881-4506
1881-4514
1881-4514
DOI:10.11272/jss.35.635