Fibrinogen and D-dimer analysis of chronic subdural hematomas and computed tomography findings: A prospective study

Abstract Objective We investigated the relationship between fibrinolytic factors and computed tomography (CT) findings in patients with chronic subdural hematomas (CSDHs). Methods Thirty-one patients with CSDHs were divided on the basis of CT findings into heterogeneous and homogeneous groups. A sample from the subdural hematoma was obtained at surgery to measure the concentrations of fibrinogen and D-dimer. Results The mean level of fibrinogen in the heterogeneous group, including the layering ( n = 4) and mixed ( n = 10) type, was 88.2 ± 121.2 mg/dL, whereas in the homogeneous group, including high density ( n = 2), isodensity ( n = 9), and low density ( n = 6) types, it was