Angiogenic Factors in Maternal Circulation and the Risk of Severe Fetal Growth Restriction

Maternal angiogenic factors (placental growth factor, soluble fms-like tyrosine kinase 1 (Flt-1), and soluble endoglin) may be associated with fetal growth restriction, and the associations may differ according to stage of pregnancy. Among children born to pregnant women without preeclampsia in Norw...

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Veröffentlicht in:American journal of epidemiology 2011-03, Vol.173 (6), p.630-639
Hauptverfasser: ASVOLD, Bjorn Olav, VATTEN, Lars J, ROMUNDSTAD, Pål R, JENUM, Pål A, ANANTH KARUMANCHI, S, ESKILD, Anne
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Sprache:eng
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Zusammenfassung:Maternal angiogenic factors (placental growth factor, soluble fms-like tyrosine kinase 1 (Flt-1), and soluble endoglin) may be associated with fetal growth restriction, and the associations may differ according to stage of pregnancy. Among children born to pregnant women without preeclampsia in Norway between 1992 and 1994, 217 singletons with severe growth restriction (small for gestational age (SGA),
ISSN:0002-9262
1476-6256
DOI:10.1093/aje/kwq373