Simple Colorimetric Method for Quantification of Surface Carboxy Groups on Polymer Particles
We present a novel, simple, and fast colorimetric method to quantify the total number of carboxy groups on polymer microparticle and nanoparticle surfaces. This method exploits that small divalent transition metal cations (M2+ = Ni2+, Co2+, Cd2+) are efficiently bound to these surface functional gro...
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| Veröffentlicht in: | Analytical chemistry (Washington) 2011-06, Vol.83 (12), p.4970-4974 |
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| container_title | Analytical chemistry (Washington) |
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| creator | Hennig, Andreas Hoffmann, Angelika Borcherding, Heike Thiele, Thomas Schedler, Uwe Resch-Genger, Ute |
| description | We present a novel, simple, and fast colorimetric method to quantify the total number of carboxy groups on polymer microparticle and nanoparticle surfaces. This method exploits that small divalent transition metal cations (M2+ = Ni2+, Co2+, Cd2+) are efficiently bound to these surface functional groups, which allows their extraction by a single centrifugation step. Remaining M2+ in the supernatant is subsequently quantified spectrophotometrically after addition of the metal ion indicator pyrocatechol violet, for which Ni2+ was identified to be the most suitable transition metal cation. We demonstrate that the difference between added and detected M2+ is nicely correlated to the number of surface carboxy groups as determined by conductometry, thereby affording a validated measure for the trueness of this procedure. The variation coefficient of ∼5% found in reproducibility studies underlines the potential of this novel method that can find conceivable applications for the characterization of different types of poly(carboxylic acid)-functionalized materials, e.g., for quality control by manufacturers of such materials. |
| doi_str_mv | 10.1021/ac2007619 |
| format | Article |
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| subjects | Analytical chemistry Cadmium - chemistry Carboxylic Acids - analysis Cations - chemistry Chemistry Cobalt - chemistry Colorimetry - methods Correlation analysis Electrochemical methods Exact sciences and technology Metals Nanoparticles Nanoparticles - chemistry Nickel - chemistry Polymers Polymers - chemistry Spectrometric and optical methods Transition Elements - chemistry |
| title | Simple Colorimetric Method for Quantification of Surface Carboxy Groups on Polymer Particles |
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