Palladium-Catalyzed Oxidative C–H Bond Coupling of Steered Acetanilides and Aldehydes: A Facile Access to ortho-Acylacetanilides

A palladium-catalyzed oxidative C–H bond functionalization/ortho-acylation of acetanilides using easily accessible aldehyde as the acyl source is described. In the presence of a Pd(TFA)2 catalyst and tert-butylhydroperoxide at 90 °C in general, an array of ortho-acylacetanilides can be afforded in g...

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Veröffentlicht in:	Organic letters 2011-06, Vol.13 (12), p.3258-3261
Hauptverfasser:	Wu, Yinuo, Li, Baozhu, Mao, Fei, Li, Xingshu, Kwong, Fuk Yee
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetanilides - chemical synthesis Acetanilides - chemistry Aldehydes - chemistry Catalysis Molecular Structure Oxidation-Reduction Palladium - chemistry Stereoisomerism
Online-Zugang:	Volltext
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