Impact of Donor-Transmitted Atherosclerosis on Early Cardiac Allograft Vasculopathy: New Findings by Three-Dimensional Intravascular Ultrasound Analysis

The influence of donor-transmitted coronary atherosclerosis (DA) on plaque progression during the first year after cardiac transplantation (Tx) is unknown. Serial 3-dimensional intravascular ultrasound (IVUS) studies were performed within 8 weeks (baseline; BL) and at 1 year after Tx in 38 recipient...

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Veröffentlicht in:	Transplantation 2011-06, Vol.91 (12), p.1406-1411
Hauptverfasser:	YAMASAKI, Masao, SAKURAI, Ryota, FEARON, William F, HIROHATA, Atsushi, HONDA, Yasuhiro, BONNEAU, Heidi N, LUIKART, Helen, YOCK, Paul G, FITZGERALD, Peter J, YEUNG, Alan C, VALANTINE, Hannah A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Arteries Arteriosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Coronary Angiography - methods Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - etiology Coronary Vessels - diagnostic imaging Disease Progression Dopamine Female Fundamental and applied biological sciences. Psychology Fundamental immunology Heart transplantation Heart Transplantation - adverse effects Heart Transplantation - diagnostic imaging Humans Longitudinal Studies Male Medical sciences Middle Aged Multivariate Analysis Plaques Prospective Studies Regression Analysis Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue Donors Tissue, organ and graft immunology Transplantation, Homologous Ultrasonography - methods Ultrasound Vascular diseases
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Zusammenfassung:	The influence of donor-transmitted coronary atherosclerosis (DA) on plaque progression during the first year after cardiac transplantation (Tx) is unknown. Serial 3-dimensional intravascular ultrasound (IVUS) studies were performed within 8 weeks (baseline; BL) and at 1 year after Tx in 38 recipients. On the basis of maximum intimal thickness (MIT) at BL, recipients were divided into DA group (DA+; MIT≥0.5 mm, n=23) or non-DA group (DA-; MIT
ISSN:	0041-1337 1534-6080
DOI:	10.1097/tp.0b013e31821ab91b