Performance of the Pediatric Index of Mortality 2 for pediatric cardiac surgery patients

To evaluate the performance of the Pediatric Index of Mortality 2 (PIM-2) for pediatric cardiac surgery patients admitted to the pediatric intensive care unit (PICU). : Retrospective cohort analysis. Multi-institutional PICUs. Children whose PICU admission had an associated cardiac surgical procedure. None. Performance of the PIM-2 was evaluated with both discrimination and calibration measures. Discrimination was assessed with a receiver operating characteristic curve and associated area under the curve measurement. Calibration was measured across defined groups based on mortality risk, using the Hosmer-Lemeshow goodness-of-fit test. Analyses were performed initially, using the entire cohort, and then based on operative status (perioperative defined as procedure occurring within 24 hrs of PICU admission and preoperative as occurring >24 hrs from the time of PICU admission). A total of 9,208 patients were identified as cardiac surgery patients with 8,391 (91%) considered as perioperative. Average age of the entire cohort was 3.3 yrs (median, 10 mos, 0-18 yrs), although preoperative children tended to be younger (median,