Postnatal neurogenesis in the hippocampal dentate gyrus and subventricular zone of the Göttingen minipig

Highlights ► Postnatal neurogenesis is important for neuroplasticity and brain repair. ► The Göttingen minipig shares anatomic and physiologic characteristics with humans. ► We examine neurogenesis in the subventricular zone and dentate gyrus of the minipig. ► We find prominent proliferation potency...

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Veröffentlicht in:Brain research bulletin 2011-05, Vol.85 (3), p.169-179
Hauptverfasser: Guidi, Sandra, Bianchi, Patrizia, Alstrup, Aage K. Olsen, Henningsen, Kim, Smith, Donald F, Bartesaghi, Renata
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container_end_page 179
container_issue 3
container_start_page 169
container_title Brain research bulletin
container_volume 85
creator Guidi, Sandra
Bianchi, Patrizia
Alstrup, Aage K. Olsen
Henningsen, Kim
Smith, Donald F
Bartesaghi, Renata
description Highlights ► Postnatal neurogenesis is important for neuroplasticity and brain repair. ► The Göttingen minipig shares anatomic and physiologic characteristics with humans. ► We examine neurogenesis in the subventricular zone and dentate gyrus of the minipig. ► We find prominent proliferation potency in juvenile as well as adult animals. ► The minipig may be a good model for studying neurogenesis in adult brain disorders.
doi_str_mv 10.1016/j.brainresbull.2011.03.028
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Animals
Animals, Newborn
Body Weight
Brain Mapping
BrdU
Bromodeoxyuridine - metabolism
Cell Count - methods
Cell Differentiation
Dentate Gyrus - cytology
Dentate Gyrus - growth & development
Germinal niches
Granule cells
Lateral Ventricles - cytology
Lateral Ventricles - growth & development
Neurogenesis
Neurogenesis - physiology
Neurology
Organ Size
Porcine brain
Stem Cell Niche - cytology
Stem Cell Niche - physiology
Stereology
Swine
Swine, Miniature
title Postnatal neurogenesis in the hippocampal dentate gyrus and subventricular zone of the Göttingen minipig
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