HPV Vaccine against HPV Infection and Disease in Males

HPV Vaccine against HPV Infection and Disease in Males

To the Editor: Giuliano et al. (Feb. 3 issue) 1 report an efficacy of 90.4% for the quadrivalent human papillomavirus (HPV) vaccine against external genital lesions (mainly condylomata acuminata) related to HPV-6, 11, 16, or 18 in healthy, predominantly heterosexual males. Men who are infected with...

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Veröffentlicht in:The New England journal of medicine 2011-06, Vol.364 (22), p.2163-2165
Hauptverfasser: Wieland, Ulrike, Kreuter, Alexander, Bansal, Vishal, Goyal, Kapil, Singh, Mini P, Harper, Diane M, Giuliano, Anna R, Palefsky, Joel M, Guris, Dalya
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Child
Condyloma acuminatum
Female
HIV
Human immunodeficiency virus
Human papillomavirus
Human papillomavirus 18 - immunology
Human papillomavirus 6 - immunology
Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18
Humans
Male
Papillomavirus Infections - prevention & control
Papillomavirus Vaccines - immunology
Penis
Vaccines
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Zusammenfassung:To the Editor: Giuliano et al. (Feb. 3 issue) 1 report an efficacy of 90.4% for the quadrivalent human papillomavirus (HPV) vaccine against external genital lesions (mainly condylomata acuminata) related to HPV-6, 11, 16, or 18 in healthy, predominantly heterosexual males. Men who are infected with the human immunodeficiency virus (HIV) and who have sex with men are at particularly high risk for persistent HPV infection and HPV-induced lesions. 2 In 640 such men who were examined at our institution, 347 (54%) presented with frequently multiple condyloma within the past 8 years, including 2.7% with oral lesions, 9.1% with penile lesions, and . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc1102684