The evaluation of the genotoxicity of two food preservatives: Sodium benzoate and potassium benzoate

In this study, the genotoxic effects of sodium benzoate (SB) and potassium benzoate (PB) were investigated in cultured human peripheral lymphocytes using chromosomal aberrations (CA), sister chromatid exchange (SCE), and micronuclei (MN). The level of nuclear DNA damage of SB and PB were also evalua...

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Veröffentlicht in:	Food and chemical toxicology 2011-04, Vol.49 (4), p.763-769
Hauptverfasser:	Zengin, N., Yüzbaşıoğlu, D., Ünal, F., Yılmaz, S., Aksoy, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzoates - toxicity Biological and medical sciences chromosome aberrations crossing over cytotoxicity DNA damage Dose-Response Relationship, Drug Food additive food preservatives Food Preservatives - toxicity Food toxicology Genotoxicity Human lymphocytes Humans lymphocytes Lymphocytes - drug effects Medical sciences mutagenicity Mutagenicity Tests nuclear genome potassium Potassium benzoate Sodium benzoate Sodium Benzoate - toxicity Toxicology
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