Incidence, Predictors and Associated Outcomes of Renal Cell Carcinoma in Long-term Dialysis Patients

We carried out an analysis of the United States Renal Data System to determine the incidence, risk factors and prognosis of renal cell carcinoma (RCC) in a national population of patients receiving incident long-term dialysis. In Cox regression, male gender, older age, end-stage renal disease caused...

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Veröffentlicht in:Urology (Ridgewood, N.J.) N.J.), 2011-06, Vol.77 (6), p.1271-1276
Hauptverfasser: Hurst, Frank P, Jindal, Rahul M, Fletcher, James J, Dharnidharka, Vikas, Gorman, Greg, Lechner, Brent, Nee, Robert, Agodoa, Lawrence Y, Abbott, Kevin C
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Sprache:eng
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Zusammenfassung:We carried out an analysis of the United States Renal Data System to determine the incidence, risk factors and prognosis of renal cell carcinoma (RCC) in a national population of patients receiving incident long-term dialysis. In Cox regression, male gender, older age, end-stage renal disease caused by obstruction, tuberous sclerosis, focal segmental glomerulosclerosis, as well as acquired renal cysts, were independently associated with RCC. Most cases of RCC in incident long-term dialysis patients occurred in patients without acquired renal cysts. A diagnosis of RCC was associated with increased risk of subsequent mortality overall and in all high-risk groups.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2011.01.007