Metabolic phenotyping for monitoring surgical patients

Metabolic phenotyping for monitoring surgical patients

Surgical metabonomics has great potential to improve the quality of surgical care delivered in the operating theatre, postoperative monitoring of patients in critical care situations, and beyond. [...] we are engaging in large-scale prospective studies into the surgical journey (figure) of patients...

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Veröffentlicht in:The Lancet (British edition) 2011-05, Vol.377 (9780), p.1817-1819
Hauptverfasser: Kinross, James M, Holmes, Elaine, Darzi, Ara W, Nicholson, Jeremy K
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biomarkers - analysis
Decision making
Disease
Humans
Internal Medicine
Mass Spectrometry
Metabolites
Metabolomics
Mortality
Nuclear Magnetic Resonance, Biomolecular
Phenotype
Prognosis
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Surgery
Surgical Procedures, Operative
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Beschreibung
Zusammenfassung:Surgical metabonomics has great potential to improve the quality of surgical care delivered in the operating theatre, postoperative monitoring of patients in critical care situations, and beyond. [...] we are engaging in large-scale prospective studies into the surgical journey (figure) of patients randomly assigned to groups defined by metabonomic analysis or by current gold standards of surgical diagnostics.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(11)60171-2