Effects of acarbose treatment on markers of insulin sensitivity and systemic inflammation

This study assessed the effect of postprandial glucose reduction by acarbose on insulin sensitivity and biomarkers of systemic inflammation. This was a single-center, double-blind, randomized, placebo-controlled, crossover study

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Bibliographische Detailangaben
Veröffentlicht in:	Diabetes technology & therapeutics 2011-06, Vol.13 (6), p.615-623
Hauptverfasser:	Rudovich, Natalia N, Weickert, Martin O, Pivovarova, Olga, Bernigau, Wolfgang, Pfeiffer, Andreas F H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acarbose Acarbose - therapeutic use Adiponectin - blood Biomarkers - blood Body Mass Index Cardiovascular Diseases - prevention & control Cross-Over Studies Cytokines - blood Development and progression Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - immunology Double-Blind Method Enzyme Inhibitors - therapeutic use Enzyme-linked immunosorbent assay Female Glucose Intolerance - blood Glucose Intolerance - complications Glucose Intolerance - drug therapy Glucose Intolerance - immunology Glycoside Hydrolase Inhibitors Health aspects Humans Hypoglycemic Agents - therapeutic use Inflammation Inflammation Mediators - blood Insulin Resistance Male Middle Aged Overweight - complications Proinsulin - blood Risk factors Severity of Illness Index
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Beschreibung
Zusammenfassung:	This study assessed the effect of postprandial glucose reduction by acarbose on insulin sensitivity and biomarkers of systemic inflammation. This was a single-center, double-blind, randomized, placebo-controlled, crossover study
ISSN:	1520-9156 1557-8593
DOI:	10.1089/dia.2010.0235