Taenia crassiceps: A secretion-substance of low molecular weight leads to disruption and apoptosis of seminiferous epithelium cells in male mice

Taenia crassiceps: A secretion-substance of low molecular weight leads to disruption and apoptosis of seminiferous epithelium cells in male mice

[Display omitted] ► A Taenia crassiceps secretion-substance of low molecular weight leads to severe pathology in testis of mice. ► Generalized apoptosis of germ cells within the seminiferous tubules. ► A significant infiltration of macrophages within seminiferous tubules. ► Deformity of sperm heads...

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Veröffentlicht in:Experimental parasitology 2011-07, Vol.128 (3), p.184-191
Hauptverfasser: Zepeda, Nadia, Copitin, Natalia, Solano, Sandra, Fernández, Ana M., Tato, Patricia, Molinari, José L.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Apoptosis
Ascitic Fluid - chemistry
Ascitic Fluid - parasitology
Biological and medical sciences
Chromatography, Gel
Cysticerci
Cysticercosis - immunology
Cysticercosis - parasitology
Cysticercosis - pathology
Cysticercus - immunology
Cysticercus - metabolism
electron microscopy
Electrophoresis, Polyacrylamide Gel
Female
Fundamental and applied biological sciences. Psychology
Germ cells
In Situ Nick-End Labeling
Leydig cells
Life cycle. Host-agent relationship. Pathogenesis
macrophages
Macrophages - pathology
Male
Mice
Mice, Inbred BALB C
Microscopy, Electron, Transmission
Molecular Weight
parasitology
Protozoa
Secretion-substance
seminiferous epithelium
Seminiferous Epithelium - pathology
Seminiferous Epithelium - ultrastructure
Seminiferous tubules
Sertoli cells
somatic cells
spermatids
Taenia crassiceps
Testis
Testis - pathology
Testis - ultrastructure
TUNEL
Ultrafiltration
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Zusammenfassung:[Display omitted] ► A Taenia crassiceps secretion-substance of low molecular weight leads to severe pathology in testis of mice. ► Generalized apoptosis of germ cells within the seminiferous tubules. ► A significant infiltration of macrophages within seminiferous tubules. ► Deformity of sperm heads cells. The present research was performed to isolate and study the effects of a low molecular weight (
ISSN:0014-4894
1090-2449
DOI:10.1016/j.exppara.2011.03.013