Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale

MLL- rearranged acute lymphoblastic leukemia (ALL) in infants (

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Bibliographische Detailangaben
Veröffentlicht in:	Leukemia 2011-03, Vol.25 (3), p.429-439
Hauptverfasser:	Stumpel, D J P M, Schotte, D, Lange-Turenhout, E A M, Schneider, P, Seslija, L, de Menezes, R X, Marquez, V E, Pieters, R, den Boer, M L, Stam, R W
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154/436/2388 631/337/176/1988 631/337/384/331 692/699/67/1990/283/2125 Acute lymphoblastic leukemia Acute lymphocytic leukemia Babies Biological and medical sciences Biology Bone marrow Cancer Research Care and treatment Children Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 4 CpG Islands Critical Care Medicine Cytidine - analogs & derivatives Cytidine - pharmacology Development and progression DNA (Cytosine-5-)-Methyltransferase 1 DNA (Cytosine-5-)-Methyltransferases - genetics DNA Methylation DNA methyltransferase DNMT1 protein Gene expression Gene Rearrangement Genes Genetic aspects Genomes Hematologic and hematopoietic diseases Hematology Histone-Lysine N-Methyltransferase Histones Homeodomain Proteins - genetics Humans Infant Infants Intensive Internal Medicine Leukemia Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphatic leukemia Medical sciences Medicine Medicine & Public Health Methylation Methyltransferases MicroRNAs MicroRNAs - genetics miRNA Myeloid-Lymphoid Leukemia Protein - genetics Oncology original-article Patients Pediatrics Physiological aspects Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Proteins Repressor Proteins - genetics Ribonucleic acid RNA Translocation, Genetic Zinc Finger E-box Binding Homeobox 2
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Beschreibung
Zusammenfassung:	MLL- rearranged acute lymphoblastic leukemia (ALL) in infants (
ISSN:	0887-6924 1476-5551
DOI:	10.1038/leu.2010.282