Single-Step Electrospinning of Bimodal Fiber Meshes for Ease of Cellular Infiltration

Bimodal fiber meshes with fiber diameters differing by one order of magnitude, are electrospun in a simple one‐step process, using a standard single syringe electrospin setup. The nano‐ and microfiber meshes combine the benefits of nanofibers (cell adhesion, proliferation) with those of microfibers...

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Veröffentlicht in:Macromolecular rapid communications. 2010-01, Vol.31 (1), p.59-64
Hauptverfasser: Gentsch, Rafael, Boysen, Bjoern, Lankenau, Andreas, Börner, Hans G.
Format: Artikel
Sprache:eng
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Zusammenfassung:Bimodal fiber meshes with fiber diameters differing by one order of magnitude, are electrospun in a simple one‐step process, using a standard single syringe electrospin setup. The nano‐ and microfiber meshes combine the benefits of nanofibers (cell adhesion, proliferation) with those of microfibers (open structure, large pore size) and are therefore interesting as scaffolds for cellular infiltration. Electrospinning has been established as a versatile method to produce diverse nonwoven materials. The simple procedure, which can be up‐scaled, allows to process synthetic and biological polymers as well as inorganics or complex composites.
ISSN:1022-1336
1521-3927
DOI:10.1002/marc.200900431