Mass screening for hypothyroidism in a cohort of HIV infected patients in a Bogotá hospital, Colombia

The objective of this study was to evaluate the frequency of thyroid function alterations and its associated factors in a group of patients from a university hospital in Colombia. From June 2007 through June 2008, 636 HIV patients were followed in order to assess the relation of thyroid function wit...

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Veröffentlicht in:	Revista chilena de infectología 2011-02, Vol.28 (1), p.59-63
Hauptverfasser:	Gómez Q, Carlos Hernando, Vesga G, Juan Fernando, Lowenstein De M, Ellen, Suárez R, Jorge Oswaldo, Gil L, Fabián Armando, Valderrama B, Sandra Liliana, Tamara, José Roberto, Castro P, Norys Alexandra, Alvarez M, Carlos Arturo
Format:	Artikel
Sprache:	spa
Schlagworte:	Adolescent Adult Aged Anti-HIV Agents - adverse effects Antiretroviral Therapy, Highly Active Cohort Studies Colombia Cross-Sectional Studies Female HIV Infections - drug therapy Hospitals, University Humans Hypothyroidism - chemically induced Hypothyroidism - diagnosis Male Middle Aged Nevirapine - adverse effects Stavudine - adverse effects Thyrotropin - blood Viral Load Young Adult
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Zusammenfassung:	The objective of this study was to evaluate the frequency of thyroid function alterations and its associated factors in a group of patients from a university hospital in Colombia. From June 2007 through June 2008, 636 HIV patients were followed in order to assess the relation of thyroid function with the use of HAART. The overall prevalence of hypothyroidism (TSH > 4.6 μUI/mL) was 15.5% (100/636). The association of hypothyroidism in the independent analysis showed significant relation only for the use of nevirapine (RR 1.6; CI 95% 1.1- 2.34) and stavudine (RR 1.5; CI 95%, 1 - 2.3). The prevalence of hypothyroidism was surprisingly high among the studied population.
ISSN:	0716-1018