Three-year follow-up in a subset of high-risk patients randomly assigned to off-pump versus on-pump coronary artery bypass surgery: the Best Bypass Surgery Trial

ObjectiveTo evaluate off-pump versus on-pump coronary artery bypass grafting (CABG) in patients with three-vessel disease and a high-risk operative profile.DesignA randomised clinical trial.SettingRigshospitalet, University Hospital, Copenhagen, Denmark.Participants341 patients with three-vessel dis...

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Veröffentlicht in:	Heart (British Cardiac Society) 2011-06, Vol.97 (11), p.907-913
Hauptverfasser:	Møller, Christian H, Perko, Mario J, Lund, Jens T, Andersen, Lars W, Kelbæk, Henning, Madsen, Jan K, Winkel, Per, Gluud, Christian, Steinbrüchel, Daniel A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences CABG Cardiac Output, Low - mortality Cardiology. Vascular system cardiopulmonary bypass Cardiovascular disease clinical trials Coronary Artery Bypass - mortality coronary artery bypass graft surgery Coronary Artery Bypass, Off-Pump - mortality Coronary Artery Disease - mortality Coronary Artery Disease - surgery Coronary heart disease Coronary vessels CPB Denmark - epidemiology Female Follow-Up Studies Heart Heart attacks Heart surgery Humans Informed consent Intubation Kinases Male Medical sciences Middle Aged Mortality Myocardial Infarction - mortality off-pump surgery Pneumonia Postoperative Complications - mortality Postoperative period Reoperation Risk Factors Stroke Stroke - mortality Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart surgery–coronary bypass Surgical techniques Treatment Outcome Ventilation
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Beschreibung
Zusammenfassung:	ObjectiveTo evaluate off-pump versus on-pump coronary artery bypass grafting (CABG) in patients with three-vessel disease and a high-risk operative profile.DesignA randomised clinical trial.SettingRigshospitalet, University Hospital, Copenhagen, Denmark.Participants341 patients with three-vessel disease and a EuroSCORE of 5 or greater. Main exclusion criteria were previous heart surgery, poor left ventricular function (ejection fraction
ISSN:	1355-6037 1468-201X
DOI:	10.1136/hrt.2010.211680