Genotoxicity of cadmium on root meristem cells of Allium cepa: cytogenetic and Comet assay approach

Cytogenetic and DNA damaging effects of cadmium (Cd) were examined through chromosome aberrations (CA) and Comet assay on the root meristem cells of Allium cepa. Root meristem cells were exposed to Cd (10, 20, and 40 μM) for 24 h and also left in water for 24 h recovery. Exposure of Cd revealed sign...

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Veröffentlicht in:	Ecotoxicology and environmental safety 2008-11, Vol.71 (3), p.711-716
Hauptverfasser:	Seth, C.S., Misra, V., Chauhan, L.K.S., Singh, R.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allium cepa Animals Cadmium Cadmium - toxicity Cell Cycle - drug effects Chromosome aberrations Chromosome Aberrations - chemically induced Comet Assay Cytogenetic Analysis DNA Damage Meristem - drug effects Meristem - genetics Meristem - growth & development Mice Micronuclei, Chromosome-Defective - chemically induced Micronucleus induction Mitotic Index Mutagens - toxicity Onions - drug effects Onions - genetics Onions - growth & development Plant Roots - drug effects Plant Roots - genetics Plant Roots - growth & development Soil Pollutants - toxicity Tail length Tail moment
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Zusammenfassung:	Cytogenetic and DNA damaging effects of cadmium (Cd) were examined through chromosome aberrations (CA) and Comet assay on the root meristem cells of Allium cepa. Root meristem cells were exposed to Cd (10, 20, and 40 μM) for 24 h and also left in water for 24 h recovery. Exposure of Cd revealed significant ( P
ISSN:	0147-6513 1090-2414
DOI:	10.1016/j.ecoenv.2008.02.003