Carboxylate-Assisted Ruthenium-Catalyzed Direct Alkylations of Ketimines
The mechanism of carboxylate-assisted ruthenium(II)-catalyzed direct alkylations of ketimines with unactivated alkyl halides was probed through experimental studies. The remarkable chemoselectivity of the broadly applicable catalyst also enabled direct alkylations among others on H2O or under solven...
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| Veröffentlicht in: | Organic letters 2011-04, Vol.13 (7), p.1875-1877 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | The mechanism of carboxylate-assisted ruthenium(II)-catalyzed direct alkylations of ketimines with unactivated alkyl halides was probed through experimental studies. The remarkable chemoselectivity of the broadly applicable catalyst also enabled direct alkylations among others on H2O or under solvent-free reaction conditions. |
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| ISSN: | 1523-7060 1523-7052 |
| DOI: | 10.1021/ol200366n |