Rett syndrome model suggests MECP2 gives neurons the quiet they need to think
The neurodevelopmental disorder Rett syndrome involves mutations in the transcriptional repressor MECP2. Two groups now show a role for MECP2 in postmitotic mouse neurons.
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| Veröffentlicht in: | Nature neuroscience 2001-04, Vol.4 (4), p.342-343 |
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| container_title | Nature neuroscience |
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| creator | Carter, Alexandre R Segal, Rosalind A |
| description | The neurodevelopmental disorder Rett syndrome involves mutations in the transcriptional repressor MECP2. Two groups now show a role for MECP2 in postmitotic mouse neurons. |
| doi_str_mv | 10.1038/85970 |
| format | Article |
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| subjects | Animal Genetics and Genomics Animals Behavioral Sciences Biological Techniques Biomedical and Life Sciences Biomedicine Care and treatment Chromosomal Proteins, Non-Histone Disease Models, Animal DNA Methylation DNA-Binding Proteins - genetics DNA-Binding Proteins - physiology Female Gene mutations Genetic aspects Health aspects Humans Male Methyl-CpG-Binding Protein 2 Mice Mutation Neurobiology Neurons Neurons - physiology Neurosciences news-and-views Physiological aspects Repressor Proteins Rett syndrome Rett Syndrome - genetics Rett Syndrome - physiopathology Risk factors |
| title | Rett syndrome model suggests MECP2 gives neurons the quiet they need to think |
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