Functional annotation of a full-length mouse cDNA collection

The RIKEN Mouse Gene Encyclopaedia Project, a systematic approach to determining the full coding potential of the mouse genome, involves collection and sequencing of full-length complementary DNAs and physical mapping of the corresponding genes to the mouse genome. We organized an international func...

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Veröffentlicht in:	Nature 2001-02, Vol.409 (6821), p.685-690
Hauptverfasser:	Kawai, J, Shinagawa, A, Shibata, K, Yoshino, M, Itoh, M, Ishii, Y, Arakawa, T, Hara, A, Fukunishi, Y, Konno, H, Adachi, J, Fukuda, S, Aizawa, K, Izawa, M, Nishi, K, Kiyosawa, H, Kondo, S, Yamanaka, I, Saito, T, Okazaki, Y, Gojobori, T, Bono, H, Kasukawa, T, Saito, R, Kadota, K, Matsuda, H, Ashburner, M, Batalov, S, Casavant, T, Fleischmann, W, Gaasterland, T, Gissi, C, King, B, Kochiwa, H, Kuehl, P, Lewis, S, Matsuo, Y, Nikaido, I, Pesole, G, Quackenbush, J, Schriml, L M, Staubli, F, Suzuki, R, Tomita, M, Wagner, L, Washio, T, Sakai, K, Okido, T, Furuno, M, Aono, H, Baldarelli, R, Barsh, G, Blake, J, Boffelli, D, Bojunga, N, Carninci, P, de Bonaldo, M F, Brownstein, M J, Bult, C, Fletcher, C, Fujita, M, Gariboldi, M, Gustincich, S, Hill, D, Hofmann, M, Hume, D A, Kamiya, M, Lee, N H, Lyons, P, Marchionni, L, Mashima, J, Mazzarelli, J, Mombaerts, P, Nordone, P, Ring, B, Ringwald, M, Rodriguez, I, Sakamoto, N, Sasaki, H, Sato, K, Schönbach, C, Seya, T, Shibata, Y, Storch, K F, Suzuki, H, Toyo-oka, K, Wang, K H, Weitz, C, Whittaker, C, Wilming, L, Wynshaw-Boris, A, Yoshida, K, Hasegawa, Y, Kawaji, H, Kohtsuki, S, Hayashizaki, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Animals BASIC BIOLOGICAL SCIENCES Biological and medical sciences Chromosome Mapping Computational Biology Deoxyribonucleic acid DNA DNA, Complementary Enzymes - genetics FUNCTIONALS Fundamental and applied biological sciences. Psychology Gene Library GENES Genes. Genome Genome Genomics Humans MICE Mice - genetics Mice, Inbred C57BL Molecular and cellular biology Molecular genetics Protein Biosynthesis Protein Structure, Tertiary RNA, Messenger Rodents Sequence Analysis, DNA
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Beschreibung
Zusammenfassung:	The RIKEN Mouse Gene Encyclopaedia Project, a systematic approach to determining the full coding potential of the mouse genome, involves collection and sequencing of full-length complementary DNAs and physical mapping of the corresponding genes to the mouse genome. We organized an international functional annotation meeting (FANTOM) to annotate the first 21,076 cDNAs to be analysed in this project. Here we describe the first RIKEN clone collection, which is one of the largest described for any organism. Analysis of these cDNAs extends known gene families and identifies new ones.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/35055500