The Clonal Selection Theory: what it really is and why modern challenges are misplaced

The Clonal Selection Theory: what it really is and why modern challenges are misplaced

Historical insight: The clonal selection theory of antibody formation has recently been subjected to challenge from many quarters. A review of its history and that of scientific theories in general points to the importance of distinguishing between the central hypotheses of a theory and its subsidia...

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Veröffentlicht in:Nature immunology 2002-09, Vol.3 (9), p.793-796
1. Verfasser: Silverstein, Arthur M
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antibody Formation
Biomedical and Life Sciences
Biomedicine
Clone Cells - immunology
Clone Cells - physiology
commentary
Humans
Immune Tolerance
Immunology
Infectious Diseases
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Beschreibung
Zusammenfassung:Historical insight: The clonal selection theory of antibody formation has recently been subjected to challenge from many quarters. A review of its history and that of scientific theories in general points to the importance of distinguishing between the central hypotheses of a theory and its subsidiary implications.
ISSN:1529-2908
1529-2916
DOI:10.1038/ni0902-793