Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human

Proteoglycans are a family of extracellular macromolecules comprised of glycosaminoglycan chains of a repeated disaccharide linked to a central core protein 1 , 2 . Proteoglycans have critical roles in chondrogenesis and skeletal development. The glycosaminoglycan chains found in cartilage proteogly...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature medicine 2007-11, Vol.13 (11), p.1363-1367
Hauptverfasser:	Hiraoka, Shuichi, Furuichi, Tatsuya, Nishimura, Gen, Shibata, Shunichi, Yanagishita, Masaki, Rimoin, David L, Superti-Furga, Andrea, Nikkels, Peter G, Ogawa, Minako, Katsuyama, Kayoko, Toyoda, Hidenao, Kinoshita-Toyoda, Akiko, Ishida, Nobuhiro, Isono, Kyoichi, Sanai, Yutaka, Cohn, Daniel H, Koseki, Haruhiko, Ikegawa, Shiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggregates Animals Biomedical and Life Sciences Biomedicine Biosynthesis Bone and Bones - embryology Bone and Bones - metabolism Bone and Bones - pathology Bones Cancer Research Cartilage Cartilage - embryology Cartilage - metabolism Cartilage - pathology Cells, Cultured Chondrocytes - metabolism Chondrocytes - pathology Chondroitin Sulfates - biosynthesis Epiphyses - embryology Epiphyses - metabolism Epiphyses - pathology Facial Bones - abnormalities Facial Bones - embryology Facial Bones - metabolism Glycoproteins Humans Infectious Diseases letter Limb Deformities, Congenital - embryology Limb Deformities, Congenital - genetics Limb Deformities, Congenital - metabolism Mammals Metabolic Diseases Metabolism Mice Mice, Knockout Mice, Transgenic Molecular Medicine Monosaccharide Transport Proteins - deficiency Monosaccharide Transport Proteins - genetics Monosaccharide Transport Proteins - physiology Mutation Neurosciences Nucleotide Transport Proteins - genetics Nucleotide Transport Proteins - physiology Rodents Sugar Sulfates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!