Carbamazepine induced DRESS syndrome
We present here an 18-yr-old male who presented with intermittent fever of moderate grade and of 15 days duration, followed by maculopapular erythematous rashes over upper and lower extremities, face, and trunk developing over 10-12 days. He was suffering from recurrent seizures since last 3 months...
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Veröffentlicht in: | Journal of the Association of Physicians of India 2010-10, Vol.58, p.634-636 |
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description | We present here an 18-yr-old male who presented with intermittent fever of moderate grade and of 15 days duration, followed by maculopapular erythematous rashes over upper and lower extremities, face, and trunk developing over 10-12 days. He was suffering from recurrent seizures since last 3 months for which he was started on carbamazepine 200mg twice daily for the past 6 weeks. He was febrile on admission. Generalized lymphadenopathy with discreet, non-matted, firm and tender inguinal lymph nodes. Patch test with 1% and 5% solution of carbamazepine was strongly positive. |
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He was suffering from recurrent seizures since last 3 months for which he was started on carbamazepine 200mg twice daily for the past 6 weeks. He was febrile on admission. Generalized lymphadenopathy with discreet, non-matted, firm and tender inguinal lymph nodes. Patch test with 1% and 5% solution of carbamazepine was strongly positive.</description><identifier>ISSN: 0004-5772</identifier><identifier>PMID: 21510116</identifier><language>eng</language><publisher>India</publisher><subject>Adolescent ; Anticonvulsants - adverse effects ; Biopsy ; Carbamazepine - adverse effects ; Dermatitis, Exfoliative - chemically induced ; Dermatitis, Exfoliative - complications ; Drug Eruptions ; Drug Hypersensitivity ; Eosinophilia - chemically induced ; Eosinophilia - complications ; Epilepsy - drug therapy ; Exanthema - chemically induced ; Exanthema - complications ; Humans ; Hyperthermia, Induced ; Lymphatic Diseases - chemically induced ; Lymphatic Diseases - complications ; Male ; Patch Tests ; Skin Tests ; Syndrome ; Treatment Outcome</subject><ispartof>Journal of the Association of Physicians of India, 2010-10, Vol.58, p.634-636</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21510116$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chauhan, Ajay</creatorcontrib><creatorcontrib>Anand, Swati</creatorcontrib><creatorcontrib>Thomas, Sindha</creatorcontrib><creatorcontrib>Subramanya, H C A</creatorcontrib><creatorcontrib>Pradhan, Gyanranjan</creatorcontrib><title>Carbamazepine induced DRESS syndrome</title><title>Journal of the Association of Physicians of India</title><addtitle>J Assoc Physicians India</addtitle><description>We present here an 18-yr-old male who presented with intermittent fever of moderate grade and of 15 days duration, followed by maculopapular erythematous rashes over upper and lower extremities, face, and trunk developing over 10-12 days. He was suffering from recurrent seizures since last 3 months for which he was started on carbamazepine 200mg twice daily for the past 6 weeks. He was febrile on admission. Generalized lymphadenopathy with discreet, non-matted, firm and tender inguinal lymph nodes. Patch test with 1% and 5% solution of carbamazepine was strongly positive.</description><subject>Adolescent</subject><subject>Anticonvulsants - adverse effects</subject><subject>Biopsy</subject><subject>Carbamazepine - adverse effects</subject><subject>Dermatitis, Exfoliative - chemically induced</subject><subject>Dermatitis, Exfoliative - complications</subject><subject>Drug Eruptions</subject><subject>Drug Hypersensitivity</subject><subject>Eosinophilia - chemically induced</subject><subject>Eosinophilia - complications</subject><subject>Epilepsy - drug therapy</subject><subject>Exanthema - chemically induced</subject><subject>Exanthema - complications</subject><subject>Humans</subject><subject>Hyperthermia, Induced</subject><subject>Lymphatic Diseases - chemically induced</subject><subject>Lymphatic Diseases - complications</subject><subject>Male</subject><subject>Patch Tests</subject><subject>Skin Tests</subject><subject>Syndrome</subject><subject>Treatment Outcome</subject><issn>0004-5772</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j8tKAzEUQLNQbK3-gsxCcDWQ5GbyWMpYH1AQrK6HJPcOjMzLpLOoX69gXZ3N4cA5Y2vOuSorY-SKXeb8yTk4AHnBVlJUgguh1-y29in4wX_T3I1UdCMukbB4eNvu90U-jpimga7Yeev7TNcnbtjH4_a9fi53r08v9f2unIWsDmUbRauipUBotYmAVigflatAkobgg4QK0HFDxkVtEDAgkQot8GA9Wtiwu7_unKavhfKhGbocqe_9SNOSG6tBgXTK_Jo3J3MJA2Ezp27w6dj8j8EP8GdH_Q</recordid><startdate>201010</startdate><enddate>201010</enddate><creator>Chauhan, Ajay</creator><creator>Anand, Swati</creator><creator>Thomas, Sindha</creator><creator>Subramanya, H C A</creator><creator>Pradhan, Gyanranjan</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201010</creationdate><title>Carbamazepine induced DRESS syndrome</title><author>Chauhan, Ajay ; Anand, Swati ; Thomas, Sindha ; Subramanya, H C A ; Pradhan, Gyanranjan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p125t-fc1f4c8ebed867c3d814ac49532e63bab2353d907e79c67d3dbdee4bf30b8ad83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Anticonvulsants - adverse effects</topic><topic>Biopsy</topic><topic>Carbamazepine - adverse effects</topic><topic>Dermatitis, Exfoliative - chemically induced</topic><topic>Dermatitis, Exfoliative - complications</topic><topic>Drug Eruptions</topic><topic>Drug Hypersensitivity</topic><topic>Eosinophilia - chemically induced</topic><topic>Eosinophilia - complications</topic><topic>Epilepsy - drug therapy</topic><topic>Exanthema - chemically induced</topic><topic>Exanthema - complications</topic><topic>Humans</topic><topic>Hyperthermia, Induced</topic><topic>Lymphatic Diseases - chemically induced</topic><topic>Lymphatic Diseases - complications</topic><topic>Male</topic><topic>Patch Tests</topic><topic>Skin Tests</topic><topic>Syndrome</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chauhan, Ajay</creatorcontrib><creatorcontrib>Anand, Swati</creatorcontrib><creatorcontrib>Thomas, Sindha</creatorcontrib><creatorcontrib>Subramanya, H C A</creatorcontrib><creatorcontrib>Pradhan, Gyanranjan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Association of Physicians of India</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chauhan, Ajay</au><au>Anand, Swati</au><au>Thomas, Sindha</au><au>Subramanya, H C A</au><au>Pradhan, Gyanranjan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Carbamazepine induced DRESS syndrome</atitle><jtitle>Journal of the Association of Physicians of India</jtitle><addtitle>J Assoc Physicians India</addtitle><date>2010-10</date><risdate>2010</risdate><volume>58</volume><spage>634</spage><epage>636</epage><pages>634-636</pages><issn>0004-5772</issn><abstract>We present here an 18-yr-old male who presented with intermittent fever of moderate grade and of 15 days duration, followed by maculopapular erythematous rashes over upper and lower extremities, face, and trunk developing over 10-12 days. He was suffering from recurrent seizures since last 3 months for which he was started on carbamazepine 200mg twice daily for the past 6 weeks. He was febrile on admission. Generalized lymphadenopathy with discreet, non-matted, firm and tender inguinal lymph nodes. Patch test with 1% and 5% solution of carbamazepine was strongly positive.</abstract><cop>India</cop><pmid>21510116</pmid><tpages>3</tpages></addata></record> |
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subjects | Adolescent Anticonvulsants - adverse effects Biopsy Carbamazepine - adverse effects Dermatitis, Exfoliative - chemically induced Dermatitis, Exfoliative - complications Drug Eruptions Drug Hypersensitivity Eosinophilia - chemically induced Eosinophilia - complications Epilepsy - drug therapy Exanthema - chemically induced Exanthema - complications Humans Hyperthermia, Induced Lymphatic Diseases - chemically induced Lymphatic Diseases - complications Male Patch Tests Skin Tests Syndrome Treatment Outcome |
title | Carbamazepine induced DRESS syndrome |
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