Systemic Treatment of Cutaneous Lichen Planus: An Update

Lichen planus (LP) is a chronic and remitting dermatosis that may be idiopathic or associated with underlying systemic diseases, such as hepatitis C virus. Although numerous cases of LP resolve spontaneously, many cases require systemic treatment. Several therapeutic advances have occurred in the la...

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Veröffentlicht in:	Cutis (New York, N.Y.) N.Y.), 2011-03, Vol.87 (3), p.129-134
Hauptverfasser:	ASCH, Sarah, GOLDENBERG, Gary
Format:	Artikel
Sprache:	eng
Schlagworte:	Acitretin - therapeutic use Biological and medical sciences Clinical Trials as Topic Dermatology Glucocorticoids - therapeutic use Humans Keratolytic Agents - therapeutic use Lichen Planus - drug therapy Lichen Planus - physiopathology Medical sciences Psoriasis. Parapsoriasis. Lichen Tetracycline - therapeutic use
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Beschreibung
Zusammenfassung:	Lichen planus (LP) is a chronic and remitting dermatosis that may be idiopathic or associated with underlying systemic diseases, such as hepatitis C virus. Although numerous cases of LP resolve spontaneously, many cases require systemic treatment. Several therapeutic advances have occurred in the last 10 years: acitretin (30 mg daily for 8 weeks) remains a first-line therapy (level B, controlled clinical trial >20 participants); systemic corticosteroids are second-line therapies (level C, clinical trial
ISSN:	0011-4162 2326-6929