Hard x-ray Zernike microscopy reaches 30 nm resolution
Since its invention in 1930, Zernike phase contrast has been a pillar in optical microscopy and more recently in x-ray microscopy, in particular for low-absorption-contrast biological specimens. We experimentally demonstrate that hard-x-ray Zernike microscopy now reaches a lateral resolution below 3...
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| Veröffentlicht in: | Opt. Lett 2011-04, Vol.36 (7), p.1269-1271 |
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| container_end_page | 1271 |
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| container_issue | 7 |
| container_start_page | 1269 |
| container_title | Opt. Lett |
| container_volume | 36 |
| creator | CHEN, Yu-Tung CHEN, Tsung-Yu YI, Jaemock CHU, Yong S LEE, Wah-Keat WANG, Cheng-Liang KEMPSON, Ivan M HWU, Y GAJDOSIK, Vincent MARGARITONDO, G |
| description | Since its invention in 1930, Zernike phase contrast has been a pillar in optical microscopy and more recently in x-ray microscopy, in particular for low-absorption-contrast biological specimens. We experimentally demonstrate that hard-x-ray Zernike microscopy now reaches a lateral resolution below 30 nm while strongly enhancing the contrast, thus opening many new research opportunities in biomedicine and materials science. |
| doi_str_mv | 10.1364/ol.36.001269 |
| format | Article |
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| subjects | Animals BASIC BIOLOGICAL SCIENCES Cell Line, Tumor Coculture Techniques Exact sciences and technology Fundamental areas of phenomenology (including applications) GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE Gold - chemistry INVENTIONS Metal Nanoparticles Mice MICROSCOPY Microscopy - methods OPENINGS OPTICAL MICROSCOPY Optics Physics Polystyrenes - chemistry RESOLUTION X-Rays |
| title | Hard x-ray Zernike microscopy reaches 30 nm resolution |
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