Drug resistance patterns in pulmonary tuberculosis

To determine the resistance patterns of mycobacterium tuberculosis (MTB) isolates among category I and II patients of pulmonary tuberculosis. This cross sectional study was conducted at the Department of Medicine, Liaquat University of Medical and Health Sciences Jamshoro, from November 2008 to Sept...

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Veröffentlicht in:	Journal of the Pakistan Medical Association 2011-03, Vol.61 (3), p.229-232
Hauptverfasser:	Khoharo, Haji Khan, Shaikh, Imran Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Distribution Antitubercular Agents - therapeutic use Bacterial diseases Bacterial diseases of the respiratory system Biological and medical sciences Cross-Sectional Studies Drug Resistance Female General aspects Human bacterial diseases Humans Infectious diseases Male Medical sciences Microbial Sensitivity Tests Middle Aged Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - isolation & purification Pakistan - epidemiology Prospective Studies Sex Distribution Sputum Tuberculosis and atypical mycobacterial infections Tuberculosis, Multidrug-Resistant - classification Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - epidemiology Tuberculosis, Multidrug-Resistant - microbiology Tuberculosis, Pulmonary - classification Tuberculosis, Pulmonary - drug therapy Tuberculosis, Pulmonary - epidemiology Tuberculosis, Pulmonary - microbiology Young Adult
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Zusammenfassung:	To determine the resistance patterns of mycobacterium tuberculosis (MTB) isolates among category I and II patients of pulmonary tuberculosis. This cross sectional study was conducted at the Department of Medicine, Liaquat University of Medical and Health Sciences Jamshoro, from November 2008 to September 2009. Patients were divided into category I and II. The sputa were collected, stained with Ziehl-Nielsen (Z-N) staining and ultimately inoculated on Lowenstein-Jensen (L-J) media for six weeks. Out of 890 pulmonary tuberculosis (PTB) patients, the growth was obtained in 285 cases. The Drug sensitivity testing (DST) for Isoniazid (INH), Rifampicin (RIF), Ethambutol (EMB) Pyrazinamide (PZA) and Streptomycin (SM) were performed. The data was analyzed on SPSS 10.0. A p-value of
ISSN:	0030-9982