Tertiary Gleason pattern 5 and oncological outcomes after radical prostatectomy

This study examined the rate of Gleason pattern 5 and the influence of tertiary Gleason pattern 5 on oncological outcomes. Four hundred sixty-six patients underwent a radical prostatectomy between 1993 and 2008. Each surgical specimen was reviewed and assessed for the tumor diameter, Gleason score (...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Japanese journal of clinical oncology 2011-04, Vol.41 (4), p.571-576
Hauptverfasser:	Hashine, Katsuyoshi, Yuasa, Akihito, Shinomori, Kensuke, Shirato, Akitomi, Ninomiya, Iku, Teramoto, Norihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Chi-Square Distribution Disease-Free Survival Follow-Up Studies Humans Kaplan-Meier Estimate Male Middle Aged Multivariate Analysis Neoplasm Staging Predictive Value of Tests Proportional Hazards Models Prostate-Specific Antigen - blood Prostatectomy - methods Prostatic Neoplasms - blood Prostatic Neoplasms - immunology Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery Recurrence Retrospective Studies Severity of Illness Index Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This study examined the rate of Gleason pattern 5 and the influence of tertiary Gleason pattern 5 on oncological outcomes. Four hundred sixty-six patients underwent a radical prostatectomy between 1993 and 2008. Each surgical specimen was reviewed and assessed for the tumor diameter, Gleason score (which was based on the 2005 International Society of Urological Pathology Consensus Conference criteria) and the percentage of Gleason pattern 5. The median patient age was 68.0 years old and the median prostate-specific antigen level was 9.28 ng/ml. A tertiary Gleason pattern 5 was present in 24.2% of patients with a Gleason score of
ISSN:	0368-2811 1465-3621
DOI:	10.1093/jjco/hyq250