Common variable immunodeficiency presenting as herpes simplex virus encephalitis

Based on these clinical and laboratory results, she was given a diagnosis of CVID and started on intravenous immunoglobulin (IVIG). Since beginning treatment, she has not experienced any infectious complications and has not required any form of antimicrobial treatment. CVID is characterized by decre...

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Veröffentlicht in:Journal of allergy and clinical immunology 2011-02, Vol.127 (2), p.541-543
Hauptverfasser: Borish, Larry, MD, Ayars, Andrew G., MD, Kirkpatrick, Charles H., MD
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container_title Journal of allergy and clinical immunology
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creator Borish, Larry, MD
Ayars, Andrew G., MD
Kirkpatrick, Charles H., MD
description Based on these clinical and laboratory results, she was given a diagnosis of CVID and started on intravenous immunoglobulin (IVIG). Since beginning treatment, she has not experienced any infectious complications and has not required any form of antimicrobial treatment. CVID is characterized by decreased qualitative and quantitative immunoglobulin levels, resulting in infections, most often by bacterial pathogens.1 The frequent concurrence of defects in T-cell immunity also predisposes patients to disseminated viral infections, particularly with herpes viruses, and to systemic fungal infections.
doi_str_mv 10.1016/j.jaci.2010.11.004
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subjects Adapter proteins
Adult
Allergy and Immunology
Antigens
Bacterial infections
Biological and medical sciences
Colleges & universities
Common Variable Immunodeficiency - complications
Encephalitis, Herpes Simplex - etiology
Female
Glucose
Herpes viruses
Humans
Immune system
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infections
Lymphocytes
Male
Medical sciences
Medical treatment
Meningitis
Middle Aged
Patients
Viral infections
title Common variable immunodeficiency presenting as herpes simplex virus encephalitis
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