Common variable immunodeficiency presenting as herpes simplex virus encephalitis
Based on these clinical and laboratory results, she was given a diagnosis of CVID and started on intravenous immunoglobulin (IVIG). Since beginning treatment, she has not experienced any infectious complications and has not required any form of antimicrobial treatment. CVID is characterized by decre...
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Veröffentlicht in: | Journal of allergy and clinical immunology 2011-02, Vol.127 (2), p.541-543 |
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creator | Borish, Larry, MD Ayars, Andrew G., MD Kirkpatrick, Charles H., MD |
description | Based on these clinical and laboratory results, she was given a diagnosis of CVID and started on intravenous immunoglobulin (IVIG). Since beginning treatment, she has not experienced any infectious complications and has not required any form of antimicrobial treatment. CVID is characterized by decreased qualitative and quantitative immunoglobulin levels, resulting in infections, most often by bacterial pathogens.1 The frequent concurrence of defects in T-cell immunity also predisposes patients to disseminated viral infections, particularly with herpes viruses, and to systemic fungal infections. |
doi_str_mv | 10.1016/j.jaci.2010.11.004 |
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Since beginning treatment, she has not experienced any infectious complications and has not required any form of antimicrobial treatment. CVID is characterized by decreased qualitative and quantitative immunoglobulin levels, resulting in infections, most often by bacterial pathogens.1 The frequent concurrence of defects in T-cell immunity also predisposes patients to disseminated viral infections, particularly with herpes viruses, and to systemic fungal infections.</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/j.jaci.2010.11.004</identifier><identifier>PMID: 21167568</identifier><identifier>CODEN: JACIBY</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adapter proteins ; Adult ; Allergy and Immunology ; Antigens ; Bacterial infections ; Biological and medical sciences ; Colleges & universities ; Common Variable Immunodeficiency - complications ; Encephalitis, Herpes Simplex - etiology ; Female ; Glucose ; Herpes viruses ; Humans ; Immune system ; Immunodeficiencies ; Immunodeficiencies. 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Since beginning treatment, she has not experienced any infectious complications and has not required any form of antimicrobial treatment. CVID is characterized by decreased qualitative and quantitative immunoglobulin levels, resulting in infections, most often by bacterial pathogens.1 The frequent concurrence of defects in T-cell immunity also predisposes patients to disseminated viral infections, particularly with herpes viruses, and to systemic fungal infections.</description><subject>Adapter proteins</subject><subject>Adult</subject><subject>Allergy and Immunology</subject><subject>Antigens</subject><subject>Bacterial infections</subject><subject>Biological and medical sciences</subject><subject>Colleges & universities</subject><subject>Common Variable Immunodeficiency - complications</subject><subject>Encephalitis, Herpes Simplex - etiology</subject><subject>Female</subject><subject>Glucose</subject><subject>Herpes viruses</subject><subject>Humans</subject><subject>Immune system</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Infections</subject><subject>Lymphocytes</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medical treatment</subject><subject>Meningitis</subject><subject>Middle Aged</subject><subject>Patients</subject><subject>Viral infections</subject><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kl2L1DAUhoMo7uzqH_BCCiJ71TFfbVIQQQa_YEFBBe9Cmp64qf3anHZw_r3pzujCXngVEp7z5pyHQ8gzRreMsvJVu22tC1tO1we2pVQ-IBtGK5WXmhcPyYbSiuWlktUZOUdsaboLXT0mZ5yxUhWl3pAvu7HvxyHb2xhs3UEW-n4ZxgZ8cAEGd8imCAjDHIafmcXsGuIEmGHopw5-Z_sQF8wSB9O17cIc8Al55G2H8PR0XpDv7999233Mrz5_-LR7e5W7gvE5L7QA1kjJal5T74V0VDGhlC5ExYWSTeWUb0DIui6Fr4SogWvPisLXTitWiQtyecyd4nizAM6mD-ig6-wA44JGF1pySssykS_uke24xCE1Z1IeTVm6kIniR8rFETGCN1MMvY0Hw6hZdZvWrLrNqtswZpLuVPT8FL3UPTT_Sv76TcDLE2DR2c5HO7iAd5zQulK3Pb4-cpCU7QNEg7f6oQkR3GyaMfy_jzf3yl0XhpB-_AUHwLt5DXJDzdd1Mda9YJQyJcsf4g_o4bIs</recordid><startdate>20110201</startdate><enddate>20110201</enddate><creator>Borish, Larry, MD</creator><creator>Ayars, Andrew G., MD</creator><creator>Kirkpatrick, Charles H., MD</creator><general>Mosby, Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20110201</creationdate><title>Common variable immunodeficiency presenting as herpes simplex virus encephalitis</title><author>Borish, Larry, MD ; Ayars, Andrew G., MD ; Kirkpatrick, Charles H., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c512t-583e1d441b2b0ff34c07137785392374d9c7fde34bb63f933be28f155fbc87193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adapter proteins</topic><topic>Adult</topic><topic>Allergy and Immunology</topic><topic>Antigens</topic><topic>Bacterial infections</topic><topic>Biological and medical sciences</topic><topic>Colleges & universities</topic><topic>Common Variable Immunodeficiency - complications</topic><topic>Encephalitis, Herpes Simplex - etiology</topic><topic>Female</topic><topic>Glucose</topic><topic>Herpes viruses</topic><topic>Humans</topic><topic>Immune system</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Infections</topic><topic>Lymphocytes</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medical treatment</topic><topic>Meningitis</topic><topic>Middle Aged</topic><topic>Patients</topic><topic>Viral infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Borish, Larry, MD</creatorcontrib><creatorcontrib>Ayars, Andrew G., MD</creatorcontrib><creatorcontrib>Kirkpatrick, Charles H., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Borish, Larry, MD</au><au>Ayars, Andrew G., MD</au><au>Kirkpatrick, Charles H., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Common variable immunodeficiency presenting as herpes simplex virus encephalitis</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><addtitle>J Allergy Clin Immunol</addtitle><date>2011-02-01</date><risdate>2011</risdate><volume>127</volume><issue>2</issue><spage>541</spage><epage>543</epage><pages>541-543</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><coden>JACIBY</coden><abstract>Based on these clinical and laboratory results, she was given a diagnosis of CVID and started on intravenous immunoglobulin (IVIG). 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subjects | Adapter proteins Adult Allergy and Immunology Antigens Bacterial infections Biological and medical sciences Colleges & universities Common Variable Immunodeficiency - complications Encephalitis, Herpes Simplex - etiology Female Glucose Herpes viruses Humans Immune system Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infections Lymphocytes Male Medical sciences Medical treatment Meningitis Middle Aged Patients Viral infections |
title | Common variable immunodeficiency presenting as herpes simplex virus encephalitis |
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