Conceptual Priming in Perceptual Identification for Patients With Alzheimer's Disease and a Patient With Right Occipital Lobectomy

Two experiments examined explicit recognition memory and perceptual and conceptual contributions to implicit perceptual-identification repetition priming for patients with Alzheimer's disease (AD) and Patient M.S. with right-occipital lobectomy. Participants read words ( perceptual encoding ) and generated words ( conceptual encoding ) from a definition and letter cue (e.g., "a vehicle for moving the injured-a "). AD patients demonstrated impaired explicit and intact implicit memory for both perceptually and conceptually encoded words. M.S. demonstrated the opposite pattern: intact explicit and impaired implicit memory in both encoding conditions. The double dissociation between AD and M.S. on implicit and explicit memory tasks is discussed in terms of a putative visual memory mechanism in the right-occipital cortex that interacts with lexical mechanisms to yield perceptual-identification priming after perceptual and conceptual encoding.