iMAT: an integrative metabolic analysis tool

iMAT is an Integrative Metabolic Analysis Tool, enabling the integration of transcriptomic and proteomic data with genome-scale metabolic network models to predict enzymes' metabolic flux, based on the method previously described by Shlomi et al. The prediction of metabolic fluxes based on high...

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Veröffentlicht in:Bioinformatics 2010-12, Vol.26 (24), p.3140-3142
Hauptverfasser: Zur, Hadas, Ruppin, Eytan, Shlomi, Tomer
Format: Artikel
Sprache:eng
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Zusammenfassung:iMAT is an Integrative Metabolic Analysis Tool, enabling the integration of transcriptomic and proteomic data with genome-scale metabolic network models to predict enzymes' metabolic flux, based on the method previously described by Shlomi et al. The prediction of metabolic fluxes based on high-throughput molecular data sources could help to advance our understanding of cellular metabolism, since current experimental approaches are limited to measuring fluxes through merely a few dozen enzymes. Availability and Implementation: http://imat.cs.tau.ac.il/ Contact: zurhadas@post.tau.ac.il; ruppin@post.tau.ac.il; tomersh@cs.technion.ac.il Supplementary information: Supplementary data are available at Bioinformatics online.
ISSN:1367-4803
1460-2059
1367-4811
DOI:10.1093/bioinformatics/btq602