Obtaining better quality final clustering by merging a collection of clusterings
Motivation: Clustering methods including k-means, SOM, UPGMA, DAA, CLICK, GENECLUSTER, CAST, DHC, PMETIS and KMETIS have been widely used in biological studies for gene expression, protein localization, sequence recognition and more. All these clustering methods have some benefits and drawbacks. We...
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Veröffentlicht in: | Bioinformatics 2010-10, Vol.26 (20), p.2645-2646 |
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Sprache: | eng |
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Zusammenfassung: | Motivation: Clustering methods including k-means, SOM, UPGMA, DAA, CLICK, GENECLUSTER, CAST, DHC, PMETIS and KMETIS have been widely used in biological studies for gene expression, protein localization, sequence recognition and more. All these clustering methods have some benefits and drawbacks. We propose a novel graph-based clustering software called COMUSA for combining the benefits of a collection of clusterings into a final clustering having better overall quality. Results: COMUSA implementation is compared with PMETIS, KMETIS and k-means. Experimental results on artificial, real and biological datasets demonstrate the effectiveness of our method. COMUSA produces very good quality clusters in a short amount of time. Availability: http://www.cs.umb.edu/∼smimarog/comusa Contact: selim.mimaroglu@bahcesehir.edu.tr |
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ISSN: | 1367-4803 1460-2059 1367-4811 |
DOI: | 10.1093/bioinformatics/btq489 |