Neurolinguistic characteristics of language production in Huntington's disease: A preliminary report
Samples of spontaneous and descriptive speech were obtained from 12 patients with Huntington's disease (HD) and 24 at risk (AR) controls. The data were assessed according to a neurolinguistic protocol. HD was identified with a significant reduction in number of words produced, a diminished leve...
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Veröffentlicht in: | Brain and language 1987-05, Vol.31 (1), p.1-10 |
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description | Samples of spontaneous and descriptive speech were obtained from 12 patients with Huntington's disease (HD) and 24 at risk (AR) controls. The data were assessed according to a neurolinguistic protocol. HD was identified with a significant reduction in number of words produced, a diminished level of syntactic complexity, reductions of melodic line, phrase length, articulatory agility, and grammatical form, and increases in paraphasic errors and word-finding difficulty. The data were interpreted in support of the hypothesis that neostriatal pathology affects linguistic processing. |
doi_str_mv | 10.1016/0093-934X(87)90056-3 |
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The data were assessed according to a neurolinguistic protocol. HD was identified with a significant reduction in number of words produced, a diminished level of syntactic complexity, reductions of melodic line, phrase length, articulatory agility, and grammatical form, and increases in paraphasic errors and word-finding difficulty. The data were interpreted in support of the hypothesis that neostriatal pathology affects linguistic processing.</description><identifier>ISSN: 0093-934X</identifier><identifier>EISSN: 1090-2155</identifier><identifier>DOI: 10.1016/0093-934X(87)90056-3</identifier><identifier>PMID: 2437992</identifier><identifier>CODEN: BRLGAZ</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Inc</publisher><subject>Aphasia - diagnosis ; Behavioral psychophysiology ; Biological and medical sciences ; Caudate Nucleus - physiopathology ; Cerebral Cortex - physiopathology ; Fundamental and applied biological sciences. Psychology ; Humans ; Huntington Disease - diagnosis ; Huntington Disease - genetics ; Huntington Disease - physiopathology ; Middle Aged ; Neural Pathways - physiopathology ; Psychology. Psychoanalysis. Psychiatry ; Psychology. 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The data were assessed according to a neurolinguistic protocol. HD was identified with a significant reduction in number of words produced, a diminished level of syntactic complexity, reductions of melodic line, phrase length, articulatory agility, and grammatical form, and increases in paraphasic errors and word-finding difficulty. The data were interpreted in support of the hypothesis that neostriatal pathology affects linguistic processing.</description><subject>Aphasia - diagnosis</subject><subject>Behavioral psychophysiology</subject><subject>Biological and medical sciences</subject><subject>Caudate Nucleus - physiopathology</subject><subject>Cerebral Cortex - physiopathology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Huntington Disease - diagnosis</subject><subject>Huntington Disease - genetics</subject><subject>Huntington Disease - physiopathology</subject><subject>Middle Aged</subject><subject>Neural Pathways - physiopathology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychology. 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Psychology</topic><topic>Humans</topic><topic>Huntington Disease - diagnosis</topic><topic>Huntington Disease - genetics</topic><topic>Huntington Disease - physiopathology</topic><topic>Middle Aged</topic><topic>Neural Pathways - physiopathology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychology. Psychophysiology</topic><topic>Putamen - physiopathology</topic><topic>Risk</topic><topic>Semantics</topic><topic>Speech Production Measurement</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gordon, William P.</creatorcontrib><creatorcontrib>Illes, Judy</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Periodicals Index Online Segment 32</collection><collection>Periodicals Index Online</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - West</collection><collection>Primary Sources Access (Plan D) - International</collection><collection>Primary Sources Access & Build (Plan A) - MEA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Midwest</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Northeast</collection><collection>Primary Sources Access (Plan D) - Southeast</collection><collection>Primary Sources Access (Plan D) - North Central</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Southeast</collection><collection>Primary Sources Access (Plan D) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - UK / I</collection><collection>Primary Sources Access (Plan D) - Canada</collection><collection>Primary Sources Access (Plan D) - EMEALA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - North Central</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - International</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - International</collection><collection>Primary Sources Access (Plan D) - West</collection><collection>Periodicals Index Online Segments 1-50</collection><collection>Primary Sources Access (Plan D) - APAC</collection><collection>Primary Sources Access (Plan D) - Midwest</collection><collection>Primary Sources Access (Plan D) - MEA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Canada</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - UK / I</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - EMEALA</collection><collection>Primary Sources Access & Build (Plan A) - APAC</collection><collection>Primary Sources Access & Build (Plan A) - Canada</collection><collection>Primary Sources Access & Build (Plan A) - West</collection><collection>Primary Sources Access & Build (Plan A) - EMEALA</collection><collection>Primary Sources Access (Plan D) - Northeast</collection><collection>Primary Sources Access & Build (Plan A) - Midwest</collection><collection>Primary Sources Access & Build (Plan A) - North Central</collection><collection>Primary Sources Access & Build (Plan A) - Northeast</collection><collection>Primary Sources Access & Build (Plan A) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - Southeast</collection><collection>Primary Sources Access (Plan D) - UK / I</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - APAC</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - MEA</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><collection>Linguistics and Language Behavior Abstracts (LLBA)</collection><jtitle>Brain and language</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gordon, William P.</au><au>Illes, Judy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurolinguistic characteristics of language production in Huntington's disease: A preliminary report</atitle><jtitle>Brain and language</jtitle><addtitle>Brain Lang</addtitle><date>1987-05-01</date><risdate>1987</risdate><volume>31</volume><issue>1</issue><spage>1</spage><epage>10</epage><pages>1-10</pages><issn>0093-934X</issn><eissn>1090-2155</eissn><coden>BRLGAZ</coden><abstract>Samples of spontaneous and descriptive speech were obtained from 12 patients with Huntington's disease (HD) and 24 at risk (AR) controls. 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subjects | Aphasia - diagnosis Behavioral psychophysiology Biological and medical sciences Caudate Nucleus - physiopathology Cerebral Cortex - physiopathology Fundamental and applied biological sciences. Psychology Humans Huntington Disease - diagnosis Huntington Disease - genetics Huntington Disease - physiopathology Middle Aged Neural Pathways - physiopathology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Putamen - physiopathology Risk Semantics Speech Production Measurement |
title | Neurolinguistic characteristics of language production in Huntington's disease: A preliminary report |
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