Neurolinguistic characteristics of language production in Huntington's disease: A preliminary report

Samples of spontaneous and descriptive speech were obtained from 12 patients with Huntington's disease (HD) and 24 at risk (AR) controls. The data were assessed according to a neurolinguistic protocol. HD was identified with a significant reduction in number of words produced, a diminished leve...

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Veröffentlicht in:Brain and language 1987-05, Vol.31 (1), p.1-10
Hauptverfasser: Gordon, William P., Illes, Judy
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Illes, Judy
description Samples of spontaneous and descriptive speech were obtained from 12 patients with Huntington's disease (HD) and 24 at risk (AR) controls. The data were assessed according to a neurolinguistic protocol. HD was identified with a significant reduction in number of words produced, a diminished level of syntactic complexity, reductions of melodic line, phrase length, articulatory agility, and grammatical form, and increases in paraphasic errors and word-finding difficulty. The data were interpreted in support of the hypothesis that neostriatal pathology affects linguistic processing.
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subjects Aphasia - diagnosis
Behavioral psychophysiology
Biological and medical sciences
Caudate Nucleus - physiopathology
Cerebral Cortex - physiopathology
Fundamental and applied biological sciences. Psychology
Humans
Huntington Disease - diagnosis
Huntington Disease - genetics
Huntington Disease - physiopathology
Middle Aged
Neural Pathways - physiopathology
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Putamen - physiopathology
Risk
Semantics
Speech Production Measurement
title Neurolinguistic characteristics of language production in Huntington's disease: A preliminary report
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