Neurolinguistic characteristics of language production in Huntington's disease: A preliminary report

Samples of spontaneous and descriptive speech were obtained from 12 patients with Huntington's disease (HD) and 24 at risk (AR) controls. The data were assessed according to a neurolinguistic protocol. HD was identified with a significant reduction in number of words produced, a diminished leve...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain and language 1987-05, Vol.31 (1), p.1-10
Hauptverfasser:	Gordon, William P., Illes, Judy
Format:	Artikel
Sprache:	eng
Schlagworte:	Aphasia - diagnosis Behavioral psychophysiology Biological and medical sciences Caudate Nucleus - physiopathology Cerebral Cortex - physiopathology Fundamental and applied biological sciences. Psychology Humans Huntington Disease - diagnosis Huntington Disease - genetics Huntington Disease - physiopathology Middle Aged Neural Pathways - physiopathology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Putamen - physiopathology Risk Semantics Speech Production Measurement
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Samples of spontaneous and descriptive speech were obtained from 12 patients with Huntington's disease (HD) and 24 at risk (AR) controls. The data were assessed according to a neurolinguistic protocol. HD was identified with a significant reduction in number of words produced, a diminished level of syntactic complexity, reductions of melodic line, phrase length, articulatory agility, and grammatical form, and increases in paraphasic errors and word-finding difficulty. The data were interpreted in support of the hypothesis that neostriatal pathology affects linguistic processing.
ISSN:	0093-934X 1090-2155
DOI:	10.1016/0093-934X(87)90056-3