Follistatin-derived peptide expression in muscle decreases adipose tissue mass and prevents hepatic steatosis

Myostatin, a member of the transforming growth factor (TGF)-β superfamily, plays a potent inhibitory role in regulating skeletal muscle mass. Inhibition of myostatin by gene disruption, transgenic (Tg) expression of myostatin propeptide, or injection of propeptide or myostatin antibodies causes a wi...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 2011-03, Vol.300 (3), p.E543-E553
Hauptverfasser: Nakatani, Masashi, Kokubo, Masahiro, Ohsawa, Yutaka, Sunada, Yoshihide, Tsuchida, Kunihiro
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Sprache:eng
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