Ion-channel drug screening galvanized

Drugs that target ion channels are used to treat a wide array of conditions. But ion channels have largely eluded modern drug discovery efforts. Recently, researchers developed a novel method for high-throughput screening of voltage-dependent sodium ion channels to improve the chances of identifying...

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Veröffentlicht in:	Nature biotechnology 2006-04, Vol.24 (4), p.415-416
1. Verfasser:	Bennett, Paul B
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Bioinformatics Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Drug Design Drug therapy Electric fields Electric Stimulation - methods Ion Channel Gating - drug effects Ion Channel Gating - physiology Ion Channels - drug effects Ion Channels - physiology Ions Life Sciences Membrane Potentials - drug effects Membrane Potentials - physiology Microscopy, Fluorescence - methods news-and-views Patch-Clamp Techniques - methods Pharmaceutical Preparations - administration & dosage R&D Research & development
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Beschreibung
Zusammenfassung:	Drugs that target ion channels are used to treat a wide array of conditions. But ion channels have largely eluded modern drug discovery efforts. Recently, researchers developed a novel method for high-throughput screening of voltage-dependent sodium ion channels to improve the chances of identifying better drugs.
ISSN:	1087-0156 1546-1696
DOI:	10.1038/nbt0406-415