An additional 136 SSLP markers typed for the AXB and BXA recombinant inbred mouse strains

The AXB and BXA recombinant inbred (RI) strain sets together are the largest RI strain resource. Although 51 such strains were constructed, 41 are now available as DNA, and 33 are available as live animals; strains AXB-7, 9, 16, 17, 21 and BXA-3, 5, 15, 18, 20, 21, 22, and 23 are extinct, and strains AXB-22, 25, and BXA-6, 10, and 19 were discarded owing to contamination. Progenitor strains A/J and C57BL/6J differ significantly in their susceptibilities to many diseases, including infectious diseases, obesity, tuberculosis, and cleft palate; hence, these RI sets are a useful tool towards the goal of identifying a gene or genes controlling such polygenic traits. We now present the strain distribution pattern (SDP) for 136 additional simple sequence length polymorphic (SSLP) loci. These loci were selected to fill gaps in the existing linkage map for these RI strain sets to improve the probability that newly mapped loci are placed at their most likely positions. The SDP for D6Nds5 replaces an earlier incorrect SDP. Additionally, a partial SDP for D7Mit70 was previously published; we provide genotyping for the remaining 11 strains and correct one mistyped strain, AXB-2. D18Mit20 was heterozygous in strain BXA-20, which may be owing to a new mutation or to residual heterozygosity. This strain is now extinct and had only been inbred to generations F31-F32 at the time of its extinction. (DBO)