Psoriasis induced by cetuximab: A paradoxical adverse effect

ABSTRACT Cetuximab, an epidermal growth factor receptor inhibitor, is a chemotherapeutical agent featuring well‐known adverse dermatological effects related to tumour‐response prognosis. In psoriasis, the epidermal growth factor receptor is overexpressed; hence, the expectation would be that an epid...

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Veröffentlicht in:	Australasian journal of dermatology 2011-02, Vol.52 (1), p.56-58
Hauptverfasser:	Mas-Vidal, Albert, Coto-Segura, Pablo, Galache-Osuna, Cristina, Santos-Juanes, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal, Humanized Antineoplastic Agents - adverse effects Biological and medical sciences Cetuximab Dermatology epidermal growth factor receptor Humans Immunomodulators Male Medical sciences Middle Aged Pharmacology. Drug treatments psoriasis Psoriasis - chemically induced Psoriasis. Parapsoriasis. Lichen Treatment Outcome
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Zusammenfassung:	ABSTRACT Cetuximab, an epidermal growth factor receptor inhibitor, is a chemotherapeutical agent featuring well‐known adverse dermatological effects related to tumour‐response prognosis. In psoriasis, the epidermal growth factor receptor is overexpressed; hence, the expectation would be that an epidermal growth factor receptor inhibitor could improve psoriatic lesions. We report a case of psoriasis induced by cetuximab, which was a surprising adverse effect.
ISSN:	0004-8380 1440-0960
DOI:	10.1111/j.1440-0960.2010.00675.x