Fast and Flexible Synthesis of Pantothenic Acid and CJ-15,801

The fast and efficient syntheses of pantothenic acid and the antiparasitic agent CJ-15,801 have been achieved starting from a common imide unit through the selective manipulation of enamide intermediates.

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Bibliographische Detailangaben
Veröffentlicht in:	Organic letters 2011-02, Vol.13 (4), p.800-803
Hauptverfasser:	Sewell, Alan L, Villa, Mathew V. J, Matheson, Mhairi, Whittingham, William G, Marquez, Rodolfo
Format:	Artikel
Sprache:	eng
Schlagworte:	Imides - chemistry Molecular Conformation Molecular Structure Pantothenic Acid - analogs & derivatives Pantothenic Acid - chemical synthesis Pantothenic Acid - chemistry Pantothenic Acid - pharmacology Plasmodium falciparum - drug effects Stereoisomerism
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Beschreibung
Zusammenfassung:	The fast and efficient syntheses of pantothenic acid and the antiparasitic agent CJ-15,801 have been achieved starting from a common imide unit through the selective manipulation of enamide intermediates.
ISSN:	1523-7060 1523-7052
DOI:	10.1021/ol103114w