Nasopharyngeal Carriage of Individual Streptococcus pneumoniae Serotypes During Pediatric Pneumonia as a Means to Estimate Serotype Disease Potential

BACKGROUND:We aimed at estimating pneumococcal serotype-specific disease potential in pediatric community-acquired alveolar pneumonia (CAAP), by comparing nasopharyngeal pneumococcal carriage during disease to carriage in healthy children. METHODS:Pneumococcal nasopharyngeal cultures were obtained f...

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Veröffentlicht in:	The Pediatric infectious disease journal 2011-03, Vol.30 (3), p.227-233
Hauptverfasser:	Greenberg, David, Givon-Lavi, Noga, Newman, Nitza, Bar-Ziv, Jacob, Dagan, Ron
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial diseases Bacterial Typing Techniques Biological and medical sciences Carrier State - microbiology Child, Preschool Human bacterial diseases Humans Infant Infant, Newborn Infectious diseases Medical sciences Nasopharynx - microbiology Pneumology Pneumonia, Pneumococcal - microbiology Respiratory system : syndromes and miscellaneous diseases Serotyping Staphylococcal infections, streptococcal infections, pneumococcal infections Streptococcus pneumoniae - classification Streptococcus pneumoniae - isolation & purification Streptococcus pneumoniae - pathogenicity
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Zusammenfassung:	BACKGROUND:We aimed at estimating pneumococcal serotype-specific disease potential in pediatric community-acquired alveolar pneumonia (CAAP), by comparing nasopharyngeal pneumococcal carriage during disease to carriage in healthy children. METHODS:Pneumococcal nasopharyngeal cultures were obtained from children 1.0 of a specific serotype being carried during disease (suggesting a higher disease potential) was observed with serotypes (by decreasing rank) 1, 5, 22F, 7F, 14, 9V, and 19A. A significant OR
ISSN:	0891-3668 1532-0987
DOI:	10.1097/INF.0b013e3181f87802