Extraction and characterization of polyclonal egg yolk antibodies (IgY) in chicken against cobra (Naja naja) venom

Extraction and characterization of polyclonal egg yolk antibodies (IgY) in chicken against cobra (Naja naja) venom

Use of polyvalent antisera of equine origin has been existing as a proven treatment against snake envenomation. The need for alternative sources for antivenom production prompted this study. Polyclonal antibodies (IgY) extracted from egg yolk after inoculation of chickens with cobra venom revealed t...

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Veröffentlicht in:Current science (Bangalore) 2010-01, Vol.98 (2), p.237-239
Hauptverfasser: Prabhu, R. Rajendra, Ramamurthy, Nalini, Mathiyalagan, A.
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Chickens
Cobra venoms
Egg yolk
Eggs
Hens
Horses
Lethal dose 50
Mice
Naja naja
RESEARCH COMMUNICATIONS
Venoms
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Zusammenfassung:Use of polyvalent antisera of equine origin has been existing as a proven treatment against snake envenomation. The need for alternative sources for antivenom production prompted this study. Polyclonal antibodies (IgY) extracted from egg yolk after inoculation of chickens with cobra venom revealed that IgY is functionally equivalent to IgG of equines in both yield and potency of venom neutralization.
ISSN:0011-3891