Congenital syphilis: Observations on laboratory diagnosis of intrauterine infection

Congenital syphilis: Observations on laboratory diagnosis of intrauterine infection

A fatal case of congenital syphilis is presented with extremely severe, but very sharply localized skin manifestations. The infant's VDRL titer was 2 tube dilutions higher than the mother's, even though the infant's serum showed an apparent absence of IgM. It appears that a detectable...

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Veröffentlicht in:The Journal of pediatrics 1969-03, Vol.74 (3), p.459-462
1. Verfasser: Ackerman, Bruce D.
Format: Artikel
Sprache:eng
Schlagworte:
Female
gamma-Globulins - analysis
Humans
Infant, Newborn
Maternal-Fetal Exchange
Pregnancy
Pregnancy Complications, Infectious
Radiography
Skin Manifestations
Syphilis
Syphilis Serodiagnosis
Syphilis, Congenital - diagnosis
Syphilis, Congenital - diagnostic imaging
Syphilis, Congenital - immunology
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Beschreibung
Zusammenfassung:A fatal case of congenital syphilis is presented with extremely severe, but very sharply localized skin manifestations. The infant's VDRL titer was 2 tube dilutions higher than the mother's, even though the infant's serum showed an apparent absence of IgM. It appears that a detectable IgM elevation in the newborn infant is not a constant finding in all types of intrauterine infection.
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(69)80204-0